Acure Radically Rejuvenating Whipped Night Cream–Preserve Youthfulness with Multi-Peptides

I prefer gel or lightweight cream moisturizers for daytime because they wear well under makeup and I like that thin consistency. At night though, I reach for a heavier nourishing moisturizer instead. Even though I have combination skin, I want to make sure I’m keeping my skin sufficiently hydrated and one good way of doing that is by using a heavier moisturizer at night. 

I’ve tried many night creams through the years, at various price points. I’m very impressed by the one I’m using now, and it’s very affordable. I first heard about Acure Radically Rejuvenating Whipped Night Cream on YouTube. It was mentioned as a dupe for the very expensive Drunk Elephant Protini Polypeptide Cream. I bought that one once before and enjoyed it, but can’t justify paying $68.00 for it again (plus, Drunk Elephant was acquired by Shiseido, which is not cruelty-free). I will discuss this more later on, but I will tell you now that I definitely think Acure’s Night Cream is a much better value compared to Drunk Elephant’s “Protini.”

Product claims directly from

Multi-peptides, ferulic acid & vitamin C, age performance.

Lightweight whipped superfood cream with multi-peptides, vitamin C, ferulic acid, glacial glycoproteins to soothe and hydrate.

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Other product details

  • Price: $19.99
  • Net weight: 1.7 oz.
  • Made in USA
  • Cruelty-free (Leaping Bunny certified)
  • Vegan
  • Formulated without parabens, sulfates, mineral oil, petrolatum, and formaldehyde
  • Shelf life: 6 months
  • Where to buy: or
    • only ships within the U.S.
    • Amazon ships internationally to over 100 countries, but not all items will ship to every country. Update your default shipping address to see items that will ship to your location.
  • Overall rating: 9/10
    • Packaging/ease of application: 9/10
    • Hydration: 10/10
    • Team player: 7/10
    • Ingredients: 10/10
    • Price: 9/10

Please note that I am not a skincare professional. I am simply an individual that enjoys learning about and using skincare products. Speak to your dermatologist or esthetician if you have any concerns.

Packaging/ease of application

Acure made a very wise choice in packaging for this night cream. It is packaged in an opaque squeeze tube. This packaging doesn’t allow any light to reach the product, and only very little air can get to it when it is being dispensed. This is important for preserving the active ingredients to make sure they remain effective while you’re using the product. The squeeze tube also makes it easy to dispense the correct amount, with minimized risk of contamination since there is no need to dip fingers into the product.

This night cream is quite a thick moisturizer. That isn’t a bad thing, but it does mean that this product isn’t the easiest to blend into the skin. It does blend in completely, but requires more effort than a lightweight moisturizer.


Acure Radically Rejuvenating Whipped Night Cream is one of the most hydrating moisturizers I’ve ever used. It was an easy decision giving this category 10/10! Since this night cream is thick, it feels like it really locks in the moisture. That hydration lasts all night. My skin still feels soft and hydrated when I wake up every morning after applying this product.

Team player

The main drawback about the thick texture of this night cream is the fact that it isn’t easy to layer immediately over other skincare products. Before night cream, my night time skincare regimen after cleansing includes toner, (sometimes) BHA exfoliant, serum, and eye cream. I prefer to get all of my skincare applied as quickly as I can so I can snuggle up in bed with my Kindle early enough to read a few chapters before going to sleep. Unfortunately, this product applies much more easily if I wait 5-10 minutes between the other steps of my routine and applying this night cream.

One way to thin this product and make it easier to apply over other products, would be to mix a serum or oil with it. I haven’t tried that myself since I prefer applying each of my skincare steps individually, but I wanted to suggest this tip for anyone interested in trying this product.


Up to this point, you might be thinking “this night cream just sounds OK…what makes it special?” The answer is found in the ingredient list!


This is a long list (33 ingredients to be exact) that looks pretty intimidating. Honestly, some of these ingredients are very sophisticated and difficult for me to understand since science has never been my strength. I will do my best to describe this product’s formula anyway!

First of all, it’s important to note that 27 of the 33 ingredients provide direct benefits to the skin. That’s 81.8%, which is much higher than average! I doubt that many of you want to read about all 27 of those ingredients, so I’ll pare it down slightly by combining the peptides:

  • Glycerin
    • Natural moisturizer
  • Cetearyl olivate & sorbitan olivate
    • Paired together, these ingredients generate liquid crystal structures that are similar to the outer layer of the skin
    • Moisturizing
    • Barrier-repairing
  • Marula seed oil
    • Improves skin hydration and smoothness
    • Reduces redness
    • Rich in fatty acids (oleic, palmitic, linoleic)
    • Contains antioxidants including vitamin E
  • Nymphaea alba root extract
    • Skin conditioner
    • Calms irritated skin
  • Peptides (there are nine unique peptide ingredients, but many of them share properties)
    • Improve elasticity and reduce wrinkles by synthesising collagen and elastin
    • Stimulate skin regeneration and healing
  • Ferulic acid
    • Antioxidant
    • Stabilizes vitamin C
  • Ascorbic glucoside
    • Stable form of vitamin C combined with glucose (breaks down to pure vitamin C)
    • Antioxidant
  • Pseudoalteromonas ferment extract
    • Protects skin from dryness and redness
    • Promotes skin regeneration and smoothness by stimulating collagen and elastin synthesis
    • Regulates oil production and reduces pore size
  • Salicylic acid
    • BHA
    • Anti-inflammatory
  • Sodium hyaluronate
    • Humectant (sodium form of hyaluronic acid)
  • Aspartic acid
    • Amino acid that hydrates the skin
  • Linoleic acid
    • Omega-6 fatty acid
    • Very important for maintaining a healthy skin barrier
    • Lightens hyperpigmentation
  • Linolenic acid
    • Omega-3 fatty acid
    • Modulates the immune response of the epidermis
    • Lightens hyperpigmentation
  • Lecithin
    • Water-binding agent
    • Has skin-restoring property
  • Sodium PCA
    • Hydrates and replenishes skin
  • PCA
    • Derived from amino acids
    • Humectant
  • Lactic acid/glycolic acid copolymer
    • Skin conditioner
  • Turmeric root extract
    • Anti-inflammatory
    • Antimicrobial
    • Potent antioxidant
    • Brightens skin

* Salicylic acid and coco-caprylate/caprate are listed together as one ingredient on the ingredient list, but I was unable to find any information on “Salicylic acid coco-caprylate/caprate” in my research, so I split it into two separate ingredients. I think Acure may have made a typo with these two ingredients.

I am very impressed by the number of beneficial ingredients in this night cream. It seems to have it all, except for my favorite ingredient (niacinamide), but I can forgive that since there are so many other rockstar ingredients in this formula!

There are five ingredients in this formula that support the formula but don’t directly benefit the skin. They are water (solvent), cetearyl alcohol (thickener), coconut alkanes (emollient), coco-caprylate/caprate (emollient), and sorbitan isostearate (emulsifier).

Lastly, there is one ingredient that could be harmful to the skin: symphytum officinale callus culture extract. I had a hard time finding detailed information on this ingredient, but it is a skin-soothing ingredient that is meant to be used short-term in small concentrations. If too much is used, it could irritate skin. Fortunately, this is the very last ingredient on the list, which means there is a very low concentration (probably not enough to be harmful for anyone).


I consider Acure to be a “high-end drugstore brand” meaning that their prices are still comparatively affordable compared to a lot of actual high-end brands, but their products tend to be more expensive than a lot of similar products available in the “drugstore” price range. Acure Radically Rejuvenating Whipped Night Cream is $19.99. I don’t mind paying that price since this is such a good quality product. I expect to pay a little more when a product has an ingredient list as impressive as this one.

While I don’t mind paying $19.99 for this product, I do wish it was slightly less expensive because I have to use more of this product than I do other moisturizers (due to the thick texture). I’m definitely going through this more quickly than I have other moisturizers recently.

Dupe for Drunk Elephant Protini Polypeptide Cream?

What is a dupe? A dupe is a more affordable alternative to an expensive product. Acure Radically Rejuvenating Whipped Night Cream of course is not an exact dupe for Drunk Elephant Protini Polypeptide Cream, but these two formulas are very similar. Most notably, they contain the same nine peptide ingredients and they’re even in the same order! There are several other ingredients that are also found in both products, but frankly there are too many to list. 

One thing I like better about the Acure night cream vs. DE’s “Protini” is that it contains vitamin C and ferulic acid (Protini doesn’t contain either of these ingredients). To be fair, the more expensive DE product contains several beneficial ingredients that the Acure dupe does not have, but they are all below the peptides and therefore those ingredients likely are at quite low concentrations.

As far as texture goes, Acure Radically Rejuvenating Whipped Night Cream is much thicker than Drunk Elephant Protini Polypeptide Cream which has a light gel-cream texture. For that reason, I think the Acure night cream is a much better choice for anyone with dry skin or looking for a more hydrating product to use at night.

Then you must take into consideration the vast difference in price; Acure Radically Rejuvenating Whipped Night Cream is less than a third of the price of Drunk Elephant Protini Polypeptide Cream!

In my opinion, there is no contest: Acure wins! And of course, Acure is 100% cruelty-free! 😉

Acure Radically Rejuvenating Whipped Night Cream doesn’t look like a glamorous product, but it really is! It was named so well, because the ingredients (especially the peptides) used in this formula truly do have a rejuvenating effect on the skin.

I would recommend this product to absolutely anyone looking for a new night cream. I think it would work so well for any skin type, especially during these cooler months when we’re exposed to a lot of dry air.

This is the first skincare product I’ve ever used from Acure. Do you have any experience with this brand? If you have, please share your experience below!


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2 thoughts on “Acure Radically Rejuvenating Whipped Night Cream–Preserve Youthfulness with Multi-Peptides

  1. Hi Lauren, I just recently started using this product and have been happy with it so far. Thanks for the suggestion of adding a serum to thin it down a bit, that is a great idea! Thanks for another wonderful review! Tammy

    • Hi Tammy, I’m so glad to hear that you’re enjoying this night cream! I hope the serum idea works well for you. It’s also an easy way to work more skin-loving ingredients into your skincare routine. 🙂


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